SCHEMBL300513

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4915235	1.00	NPC1 (0.46)	NPC1HTTHCAR2KMT2ATSHR
	SCHEMBL14258958	0.89	NPC1 (0.47)	NPC1HTTAKR1C3AKR1C1ALDH1A1
	SCHEMBL4912008	0.86	CYP1A2 (0.50)	NPC1HTTHCAR2KMT2ATSHR
	SCHEMBL4223942	0.86	CYP1A2 (0.50)	NPC1HTTHCAR2KMT2ATSHR
	SCHEMBL176863	0.84	NPC1 (0.43)	NPC1HTTKMT2AAKR1C3AKR1C1
	SCHEMBL176864	0.84	NPC1 (0.43)	NPC1HTTKMT2AAKR1C3AKR1C1
	SCHEMBL176623	0.81	NPC1 (0.46)	NPC1HTTCNR1CNR2
	SCHEMBL176622	0.81	NPC1 (0.46)	NPC1HTTCNR1CNR2
	SCHEMBL176483	0.80	CNR1 (0.56)	NPC1HTTALDH1A1LMNACNR1
	SCHEMBL176790	0.80	CNR1 (0.56)	NPC1HTTALDH1A1LMNACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.