Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24809172 | 1.00 | KMT2A (0.41) | KMT2AHPGDGAADDB1CRBN | |
| SCHEMBL24569478 | 0.87 | KMT2A (0.44) | KMT2AHPGDGAADDB1CRBN | |
| SCHEMBL29887844 | 0.87 | KMT2A (0.44) | KMT2AHPGDGAADDB1CRBN | |
| SCHEMBL24810325 | 0.83 | GRM5 (0.41) | GRM5 | |
| SCHEMBL30050278 | 0.81 | KMT2A (0.40) | KMT2AHPGDGAADDB1CRBN | |
| SCHEMBL31475878 | 0.81 | HCAR3 (0.36) | KMT2AHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL24807834 | 0.81 | KMT2A (0.41) | KMT2AHPGDGAADDB1CRBN | |
| SCHEMBL30050459 | 0.81 | KMT2A (0.41) | KMT2AHPGDGAADDB1CRBN | |
| SCHEMBL23750168 | 0.80 | KMT2A (0.46) | KMT2AHPGDGAADDB1CRBN | |
| SCHEMBL29935801 | 0.80 | KMT2A (0.46) | KMT2AHPGDGAADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320383-A | Nitrogen-containing heteroaryl compound, and preparation method and application thereof | 北京鞍石生物科技股份有限公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2022269531-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2022-12-29 | — | — | WO | disclosed |