Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.67 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729667 | 0.97 | DPP3 (0.64) | DPP3CTSCBCHEDPP4CYP2C19 | |
| SCHEMBL30051406 | 0.93 | DPP3 (0.58) | DPP3BCHEDPP4CYP2C19CAPN1 | |
| SCHEMBL30052939 | 0.93 | DPP3 (0.59) | DPP3BCHEDPP4CYP2C19CAPN1 | |
| SCHEMBL31198206 | 0.92 | DPP3 (0.60) | DPP3CTSCBCHEDPP4CYP2C19 | |
| SCHEMBL29420134 | 0.91 | DPP3 (0.57) | DPP3BCHEDPP4CYP2C19CAPN1 | |
| SCHEMBL30051339 | 0.90 | DPP4 (0.58) | DPP3BCHEDPP4CYP2C19 | |
| SCHEMBL30051552 | 0.90 | DPP3 (0.56) | DPP3BCHEDPP4CAPN1CTSB | |
| SCHEMBL29380301 | 0.88 | CAPN1 (0.58) | DPP3BCHECAPN1CTSBMMP2 | |
| SCHEMBL32681277 | 0.88 | CAPN1 (0.59) | DPP3BCHECAPN1CTSBMMP2 | |
| SCHEMBL29966903 | 0.88 | DPP4 (0.54) | DPP3BCHEDPP4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12622975-B2 | Peptide-conjugated prodrugs | BRANDEIS UNIVERSITY (US) | 2026-05-12 | — | — | US | disclosed |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622975-B2 | Peptide-conjugated prodrugs | PEPD, PAM, VIP | DPP3 25/4885CTSC 131/4885BCHE 353/4885 |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | VIP, DNPEP, PEPD | DPP3 64/4885CTSC 37/4885BCHE 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.