Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174313 | 1.00 | KMT2A (0.56) | KMT2APARP1PPARGPPARASTAT3 | |
| SCHEMBL14876467 | 0.81 | GAA (0.51) | KMT2APARP1KDM4EALDH1A1MEN1 | |
| SCHEMBL3169119 | 0.81 | KMT2A (0.57) | KMT2APPARGPPARASTAT3KDM4E | |
| SCHEMBL13065371 | 0.80 | KMT2A (0.56) | KMT2APPARGPPARASTAT3KDM4E | |
| SCHEMBL12875609 | 0.80 | KMT2A (0.56) | KMT2APPARGPPARASTAT3KDM4E | |
| SCHEMBL20037232 | 0.80 | KMT2A (0.56) | KMT2APPARGPPARASTAT3KDM4E | |
| SCHEMBL3913002 | 0.79 | ALDH1A1 (0.52) | KMT2AKDM4EALDH1A1MEN1LMNA | |
| SCHEMBL29612923 | 0.79 | ALDH1A1 (0.52) | KMT2AKDM4EALDH1A1MEN1LMNA | |
| SCHEMBL2777064 | 0.76 | STAT3 (0.67) | KMT2APPARGPPARASTAT3KDM4E | |
| SCHEMBL15157114 | 0.76 | HTR2C (0.57) | KMT2APPARGPPARAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125914-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-115427044-A | Pyrrolopyrimidines as complement inhibitors | 拜奥克里斯特制药公司 | 2022-12-02 | — | — | CN | disclosed |