Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167386 | 1.00 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL30081006 | 0.86 | KMT2A (0.60) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL6128121 | 0.82 | KDM4E (0.62) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL30289846 | 0.80 | KMT2A (0.62) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL24931695 | 0.79 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL30289840 | 0.79 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL30289855 | 0.79 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL3319211 | 0.78 | KDM4E (0.56) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL29533227 | 0.78 | KDM4E (0.56) | MEN1KMT2ASMN1; SMN2POLBTSHR | |
| SCHEMBL14072478 | 0.78 | KDM4E (0.56) | MEN1KMT2ASMN1; SMN2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334305-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236101-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY (US) | 2022-11-10 | — | — | WO | disclosed |