Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289846 | 0.86 | KMT2A (0.62) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL30289855 | 0.85 | MEN1 (0.60) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL30289960 | 0.82 | MAPT (0.47) | MEN1KMT2APOLBSMN1; SMN2HTT | |
| SCHEMBL30289806 | 0.80 | MAPT (0.45) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL27167386 | 0.79 | MEN1 (0.61) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL30054584 | 0.79 | MEN1 (0.61) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL30289833 | 0.79 | MAPT (0.52) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL30081006 | 0.78 | KMT2A (0.60) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL30289854 | 0.76 | KDM4E (0.71) | MEN1KMT2APOLBSMN1; SMN2KDM4E | |
| SCHEMBL30289904 | 0.75 | MAPT (0.52) | MEN1KMT2APOLBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |