Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25182057 | 0.88 | CASP3 (0.53) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL29709555 | 0.88 | CASP3 (0.53) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL24414068 | 0.88 | CASP3 (0.53) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL29855001 | 0.87 | CASP3 (0.52) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL15083245 | 0.87 | CASP3 (0.52) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL14751345 | 0.87 | MDM4 (0.47) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL18016104 | 0.87 | MDM4 (0.47) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL16289027 | 0.87 | CASP3 (0.52) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL30278741 | 0.87 | CASP3 (0.52) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL14459910 | 0.86 | MDM4 (0.46) | MDM4TP53CASP3KMT2AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234852-A1 | PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |