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SCHEMBL300562

SCHEMBL300562

CCOC(=O)O[C@@H]1C2CCC(C2)[C@@H]1NC(=O)c1nn(-c2ccc(F)cc2F)c2c1CCCCC2Cc1ccc(F)cc1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 20/20 0.42
▸ CNR1 P21554 11/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300717 0.95 CNR2 (0.41) CNR2CNR1
SCHEMBL176429 0.89 CNR2 (0.43) CNR2CNR1
SCHEMBL300683 0.86 CNR2 (0.33) CNR2CNR1
SCHEMBL4712180 0.85 CNR2 (0.39) CNR2CNR1
SCHEMBL4221123 0.84 CNR2 (0.47) CNR2CNR1
SCHEMBL176507 0.83 CNR2 (0.42) CNR2CNR1
SCHEMBL300572 0.82 CNR2 (0.40) CNR2CNR1
SCHEMBL300707 0.82 KCNJ6 (0.33) CNR2CNR1
SCHEMBL4208017 0.78 CNR2 (0.45) CNR2CNR1
SCHEMBL3469098 0.78 CNR2 (0.40) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937259-B1 HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-11-23 — — EP claimed