Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 3/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300683 | 0.92 | CNR2 (0.33) | KCNJ6KCNJ3KCNJ5CNR2CNR1 | |
| SCHEMBL176657 | 0.89 | KCNJ6 (0.35) | KCNJ6KCNJ3KCNJ5CNR2PDE9A | |
| SCHEMBL300717 | 0.88 | CNR2 (0.41) | CNR2CNR1 | |
| SCHEMBL4209447 | 0.84 | CHRNB2 (0.36) | KCNJ6KCNJ3KCNJ5CNR2PDE9A | |
| SCHEMBL3469281 | 0.84 | NR1H4 (0.32) | KCNJ6KCNJ3KCNJ5CNR2PDE9A | |
| SCHEMBL176605 | 0.84 | NR1H4 (0.32) | KCNJ6KCNJ3KCNJ5CNR2PDE9A | |
| SCHEMBL3469214 | 0.84 | NR1H4 (0.32) | KCNJ6KCNJ3KCNJ5CNR2PDE9A | |
| SCHEMBL300562 | 0.82 | CNR2 (0.42) | CNR2CNR1 | |
| SCHEMBL176691 | 0.81 | CNR1 (0.41) | CNR2ALDH1A1LMNAHPGDCNR1 | |
| SCHEMBL176688 | 0.81 | CNR1 (0.41) | CNR2ALDH1A1LMNAHPGDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |