SCHEMBL30057745

SCHEMBL30057745

COCn1ccc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.61
CCND1 P24385 4/20 0.61
HTR2A P28223 1/20 0.53
HTR2C P28335 1/20 0.53
KMT2A Q03164 2/20 0.50
HTR6 P50406 3/20 0.47
MAPK1 P28482 2/20 0.46
HTT P42858 1/20 0.46
LMNA P02545 1/20 0.46
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
USP2 O75604 1/20 0.43
SMPD1 P17405 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6469417 1.00 CDK4 (0.61) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL30630289 0.81 CDK4 (0.68) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL2080600 0.81 CDK4 (0.68) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL20417796 0.81 CDK4 (0.57) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL31083788 0.78 CDK4 (0.70) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL3995842 0.78 CDK4 (0.70) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL1629560 0.77 CDK4 (0.68) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL29433250 0.77 CDK4 (0.68) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL3434514 0.77 HTT (0.55) CDK4CCND1HTR2AHTR2CKMT2A
SCHEMBL27467119 0.77 KMT2A (0.56) CDK4CCND1HTR2AHTR2CKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527022-B Asymmetric polysulfide compound and its synthesis method and use 华东师范大学 2022-12-06 CN disclosed