Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30057645 | 0.83 | BCL2L1 (0.50) | FFAR1DPP4MEN1CYP2D6CYP2C9 | |
| SCHEMBL7869067 | 0.82 | PTGS2 (0.59) | DPP4MEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8238614 | 0.82 | PTGS2 (0.59) | DPP4MEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3621002 | 0.82 | PTGS2 (0.59) | DPP4MEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23904583 | 0.81 | HDAC4 (0.51) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL431704 | 0.81 | HDAC4 (0.51) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL29440623 | 0.81 | HDAC4 (0.51) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL2597751 | 0.81 | HDAC4 (0.51) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL2745696 | 0.81 | PTGS2 (0.57) | DPP4MEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30058139 | 0.81 | AKR1C2 (0.49) | DHODHMEN1CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848430-B | Synthetic method of 2- ([ 1,1' -biphenyl ] -4-yl) -2-glycine compound | 马鞍山诺恩特医药科技有限公司 | 2022-12-09 | — | — | CN | disclosed |