Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NNMT | P40261 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29779525 | 0.92 | KDM4E (0.52) | KDM4EMAPTGAANNMTPLAU | |
| SCHEMBL12486871 | 0.90 | KDM4E (0.73) | KDM4EMAPTGAANNMTPLAU | |
| SCHEMBL30011603 | 0.90 | KDM4E (0.73) | KDM4EMAPTGAANNMTPLAU | |
| SCHEMBL6137536 | 0.86 | KDM4E (0.67) | KDM4EMAPTGAANNMTPLAU | |
| SCHEMBL4051485 | 0.81 | KDM4E (0.58) | KDM4EMAPTNNMTPLAUCA12 | |
| SCHEMBL29779540 | 0.81 | KDM4E (0.58) | KDM4EMAPTNNMTPLAUCA12 | |
| Trifluoroacetic Acid SCHEMBL7423059 | 0.80 | ALDH1A1 (0.54) | MAPTALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL8141928 | 0.80 | ALDH1A1 (0.59) | MAPTGAAPLAUALDH1A1LMNA | |
| SCHEMBL19691206 | 0.79 | KDM4E (0.57) | KDM4EMAPTNNMTPLAUCA12 | |
| SCHEMBL45202 | 0.79 | KDM4E (1.00) | KDM4EMAPTGAANNMTPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434472-B2 | Agent for removing undifferentiated iPS cells | Sumitomo Pharma Co., Ltd. (JP) | 2022-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434472-B2 | Agent for removing undifferentiated iPS cells | SALL4, NR4A2, NES | KDM4E 304/4885MAPT 4069/4885GAA 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.