Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.53 |
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.51 |
| ▸ | AXL | P30530 | 4/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | IL1B | P01584 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729386 | 0.86 | CRBN (0.72) | STAT3CRBNDDB1MAP1LC3BAXL | |
| SCHEMBL2382757 | 0.85 | CRBN (0.60) | STAT3CRBNDDB1MAP1LC3BAXL | |
| SCHEMBL30036545 | 0.84 | CRBN (0.75) | STAT3CRBNDDB1 | |
| SCHEMBL27944617 | 0.84 | CRBN (0.59) | STAT3CRBNDDB1MAP1LC3BAXL | |
| SCHEMBL26147901 | 0.84 | CRBN (0.59) | STAT3CRBNDDB1MAP1LC3BAXL | |
| SCHEMBL27925252 | 0.84 | CRBN (0.59) | STAT3CRBNDDB1MAP1LC3BAXL | |
| SCHEMBL23705758 | 0.84 | CRBN (0.62) | STAT3CRBNDDB1MAP1LC3BAXL | |
| SCHEMBL27925246 | 0.84 | CRBN (0.59) | STAT3CRBNDDB1MAP1LC3BAXL | |
| SCHEMBL22959613 | 0.84 | CRBN (0.59) | STAT3CRBNDDB1MAP1LC3BAXL | |
| SCHEMBL21602681 | 0.84 | CRBN (0.64) | STAT3CRBNDDB1MAP1LC3BIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097096-A2 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |