Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 4/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 14/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 14/20 | 0.39 |
| ▸ | TSHR | P16473 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30060440 | 0.89 | METTL3 (0.42) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL29772309 | 0.86 | CYP1A2 (0.38) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL29772290 | 0.83 | METTL3 (0.37) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL23313891 | 0.83 | METTL3 (0.37) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL30106842 | 0.83 | METTL3 (0.37) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL29772295 | 0.83 | METTL3 (0.48) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL23313008 | 0.83 | METTL3 (0.48) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL29772294 | 0.83 | METTL3 (0.48) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL29805335 | 0.80 | METTL3 (0.41) | METTL3PRMT5WDR77CYP1A2CYP3A4 | |
| SCHEMBL25015920 | 0.80 | METTL3 (0.38) | METTL3PRMT5WDR77CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298179-A | METTL3 modulators | 埃克森特治疗公司 | 2022-11-04 | — | — | CN | disclosed |