SCHEMBL3005883

SCHEMBL3005883

CC1(CCCCOP(=O)(O)OP(=O)(O)O)CO1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 3/20 0.46
MVD P53602 2/20 0.38
GGPS1 O95749 4/20 0.38
LPAR3 Q9UBY5 3/20 0.36
LPAR1 Q92633 2/20 0.36
LPAR2 Q9HBW0 2/20 0.36
FNTA P49354 3/20 0.33
PGGT1B P53609 2/20 0.33
FNTB P49356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3002864 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL3005196 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL2993317 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL2999226 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL3004732 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL2999121 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL3004918 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL2995236 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL2995155 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1
SCHEMBL2996806 0.98 BTN3A1 (0.45) BTN3A1MVDGGPS1LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2222647-A1 FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS Cephalon, Inc. (US) 2010-09-01 EP disclosed
WO-2010049438-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS FOR THE TREATMENT OF DISEASES INNATE PHARMA (FR) 2010-05-06 WO disclosed
EP-2150258-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS TOGETHER WITH INTERLEUKIN-2 FOR THE TREATMENT OF CANCER Innate Pharma S.A. (FR) 2010-02-10 EP disclosed
WO-2008146167-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS TOGETHER WITH INTERLEUKIN-2 FOR THE TREATMENT OF CANCER INNATE PHARMA S.A. (FR) 2008-12-04 WO disclosed
US-7432253-B2 Phosphoepoxides, method for making same and uses INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2008-10-07 US disclosed
WO-2008051547-A1 FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS CEPHALON, INC. (US) 2008-05-02 WO disclosed
US-20060287274-A1 Phosphoepoxides, method for making same and uses INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2006-12-21 US disclosed
EP-1720567-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA Innate Pharma (FR) 2006-11-15 EP disclosed
US-7101711-B1 Phosphoepoxides, method for making same and uses INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (FR) 2006-09-05 US disclosed
EP-1569656-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE Innate Pharma (FR) 2005-09-07 EP disclosed
WO-2005077411-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA INNATE PHARMA (FR) 2005-08-25 WO disclosed
WO-2004050096-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2004-06-17 WO disclosed
EP-1109818-A1 PHOSPHOEPOXIDES, METHOD FOR MAKING SAME AND USES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2001-06-27 EP disclosed
WO-2000012519-A1 PHOSPHOEPOXIDES, METHOD FOR MAKING SAME AND USES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2000-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287274-A1 Phosphoepoxides, method for making same and uses CD4, CCR9, BCL9 BTN3A1 315/4885MVD 780/4885GGPS1 2332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.