SCHEMBL2999121

SCHEMBL2999121

CC1(CCCCCCCCCCCCCCCCCCCOP(=O)(O)OP(=O)(O)O)CO1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 3/20 0.45
LPAR3 Q9UBY5 6/20 0.39
LPAR2 Q9HBW0 5/20 0.39
LPAR1 Q92633 4/20 0.39
GGPS1 O95749 4/20 0.37
MVD P53602 2/20 0.37
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3002864 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL3004975 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL3004918 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL2999226 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL3004732 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL3005196 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL2993317 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL2995236 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL2995155 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1
SCHEMBL3005228 1.00 BTN3A1 (0.45) BTN3A1LPAR3LPAR2LPAR1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject INNATE PHARMA, S.A. (FR) 2010-10-07 US disclosed
US-20100189681-A1 Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer INNATE PHARMA S.A. (FR) 2010-07-29 US disclosed
WO-2010049438-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS FOR THE TREATMENT OF DISEASES INNATE PHARMA (FR) 2010-05-06 WO disclosed
EP-1569656-B1 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2010-03-03 EP disclosed
EP-2150258-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS TOGETHER WITH INTERLEUKIN-2 FOR THE TREATMENT OF CANCER Innate Pharma S.A. (FR) 2010-02-10 EP disclosed
US-20100029674-A1 Methods of Using Phosphoantigen for the Treatment of Cancer INNATE PHARMA, S.A. (FR) 2010-02-04 US disclosed
US-20090304688-A1 Methods and Compositions for Increasing the Efficiency of Therapeutic Antibodies Using Gamma Delta T Cell Activators INNATE PHARMA S.A. (FR) 2009-12-10 US disclosed
EP-2083830-A1 IMPROVED METHODS OF USING PHOSPHOANTIGEN FOR THE TREATMENT OF CANCER Innate Pharma (FR) 2009-08-05 EP disclosed
EP-2040750-A2 METHODS AND COMPOSITIONS FOR INCREASING THE EFFICIENCY OF THERAPEUTIC ANTIBODIES USING GAMMA DELTA T CELL ACTIVATORS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2009-04-01 EP disclosed
WO-2008059052-A9 IMPROVED METHODS OF USING PHOSPHOANTIGEN FOR THE TREATMENT OF CANCER INNATE PHARMA (FR) 2009-03-12 WO disclosed
WO-2007057440-A2 IMPROVED METHODS OF USING PHOSPHOANTIGEN FOR THE TREATMENT OF CANCER INNATE PHARMA (FR) 2007-05-24 WO disclosed
WO-2007039635-A2 PHOSPHOANTIGEN SALTS OF ORGANIC BASES AND METHODS FOR THEIR CRYSTALLIZATION INNATE PHARMA (FR) 2007-04-12 WO disclosed
US-20060287274-A1 Phosphoepoxides, method for making same and uses INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2006-12-21 US disclosed
EP-1720567-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA Innate Pharma (FR) 2006-11-15 EP disclosed
US-7101711-B1 Phosphoepoxides, method for making same and uses INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (FR) 2006-09-05 US disclosed
US-20060194755-A1 Compositions and methods for regulating an immune response in a subject INNATE PHARMA, S.A.S. (FR) 2006-08-31 US disclosed
WO-2005077411-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA INNATE PHARMA (FR) 2005-08-25 WO disclosed
EP-1109818-B1 PHOSPHOEPOXIDES, METHOD FOR MAKING SAME AND USES INST NAT SANTE RECH MED (FR) 2002-11-06 EP disclosed
EP-1109818-A1 PHOSPHOEPOXIDES, METHOD FOR MAKING SAME AND USES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2001-06-27 EP disclosed
WO-2000012519-A1 PHOSPHOEPOXIDES, METHOD FOR MAKING SAME AND USES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2000-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject IFNG, IL2, ICOS BTN3A1 288/4885LPAR3 1385/4885LPAR2 1444/4885
US-20060287274-A1 Phosphoepoxides, method for making same and uses CD4, CCR9, BCL9 BTN3A1 315/4885LPAR3 868/4885LPAR2 749/4885
US-20100029674-A1 Methods of Using Phosphoantigen for the Treatment of Cancer CD4, CD74, TP53 BTN3A1 536/4885LPAR3 1706/4885LPAR2 1894/4885
US-20100189681-A1 Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer IL2, IL2RA, CD4 BTN3A1 539/4885LPAR3 1798/4885LPAR2 580/4885
US-20060194755-A1 Compositions and methods for regulating an immune response in a subject IFNG, IL2, ICOS BTN3A1 279/4885LPAR3 1486/4885LPAR2 1736/4885
US-20090304688-A1 Methods and Compositions for Increasing the Efficiency of Therapeutic Antibodies Using Gamma Delta T Cell Activators CD4, FCGR3B, IFNG BTN3A1 135/4885LPAR3 830/4885LPAR2 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.