Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.44 |
| ▸ | PRKACA | P17612 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704897 | 1.00 | CYP3A4 (0.53) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL28939613 | 0.92 | CYP3A4 (0.51) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL23704817 | 0.91 | CYP3A4 (0.51) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL30059003 | 0.90 | CYP3A4 (0.50) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL23705043 | 0.90 | CYP3A4 (0.50) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL23714846 | 0.90 | WNT3A (0.51) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL30058825 | 0.89 | CYP3A4 (0.49) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL23714972 | 0.89 | CYP3A4 (0.49) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL23704778 | 0.89 | MAPT (0.47) | CYP3A4ROCK1PRKACAALDH1A1MAPT | |
| SCHEMBL30058923 | 0.89 | MAPT (0.47) | CYP3A4ROCK1PRKACAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096657-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |