Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.59 |
| ▸ | DRD3 | P35462 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958473 | 1.00 | DRD2 (0.59) | DRD2DRD3MAPTNFKB1THPO | |
| SCHEMBL3316692 | 1.00 | DRD2 (0.59) | DRD2DRD3MAPTNFKB1THPO | |
| SCHEMBL30057164 | 1.00 | DRD2 (0.59) | DRD2DRD3MAPTNFKB1THPO | |
| SCHEMBL754233 | 1.00 | DRD2 (0.59) | DRD2DRD3MAPTNFKB1THPO | |
| SCHEMBL30058138 | 1.00 | DRD2 (0.59) | DRD2DRD3MAPTNFKB1THPO | |
| Hydrochloric Acid SCHEMBL754377 | 0.98 | DRD2 (0.57) | DRD2DRD3MAPTNFKB1THPO | |
| Bromide SCHEMBL30426257 | 0.98 | DRD2 (0.57) | DRD2DRD3MAPTNFKB1THPO | |
| Hydrochloric Acid SCHEMBL754376 | 0.98 | DRD2 (0.57) | DRD2DRD3MAPTNFKB1THPO | |
| Bromide SCHEMBL29016368 | 0.98 | DRD2 (0.57) | DRD2DRD3MAPTNFKB1THPO | |
| Hydrochloric Acid SCHEMBL30059645 | 0.98 | DRD2 (0.57) | DRD2DRD3MAPTNFKB1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117867045-A | Method for synthesizing (S) -5, 7-difluoro-1, 2,3, 4-tetrahydronaphthalene-2-amine by biological enzyme method | 中国科学院青岛生物能源与过程研究所 | 2024-04-12 | — | — | CN | claimed |
| CN-113527108-B | Process for preparing optically pure 5, 7-difluoro-1, 2,3, 4-tetrahydronaphthalen-2-amine and salts thereof | 斯芬克司药物研发（天津）股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-113527108-B | Process for preparing optically pure 5, 7-difluoro-1, 2,3, 4-tetrahydronaphthalen-2-amine and salts thereof | 斯芬克司药物研发（天津）股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-113527108-B | Process for preparing optically pure 5, 7-difluoro-1, 2,3, 4-tetrahydronaphthalen-2-amine and salts thereof | 斯芬克司药物研发（天津）股份有限公司 | 2022-10-25 | — | — | CN | disclosed |