SCHEMBL30061253

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(N)=O)C(C)C)C(C)C)[C@@H](C)O

nearest known ligand 0.54

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	F2	P00734	2/20	0.54

▸	OPRD1	P41143	5/20	0.53

▸	OPRM1	P35372	2/20	0.53

▸	OPRK1	P41145	2/20	0.53

▸	GLP1R	P43220	4/20	0.52

▸	IL23R	Q5VWK5	4/20	0.51

▸	TFPI	P10646	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30974333	0.86	F2 (0.60)	F2OPRD1OPRM1OPRK1TFPI
SCHEMBL31257052	0.86	OPRM1 (0.58)	F2OPRD1OPRM1OPRK1GLP1R
SCHEMBL13209217	0.86	IL23R (0.61)	IL23RTFPI
SCHEMBL30512499	0.86	F2 (0.51)	F2OPRD1OPRM1OPRK1IL23R
SCHEMBL30712902	0.86	GLP1R (0.58)	OPRD1OPRM1OPRK1GLP1RTFPI
SCHEMBL13254722	0.85	IL23R (0.54)	OPRD1OPRM1OPRK1IL23RTFPI
SCHEMBL31613782	0.84	NPY4R (0.54)	—
SCHEMBL30558191	0.84	F2 (0.52)	F2OPRD1OPRM1OPRK1
SCHEMBL31510397	0.84	BACE1 (0.60)	F2
SCHEMBL30906473	0.84	OPRL1 (0.52)	F2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220356218-A1	METHODS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISORDERS AND ALZHEIMER'S DISEASE AND IMPROVING NORMAL MEMORY	UNIV CALIFORNIA (US)	2022-11-10	—	—	US	disclosed