Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695270 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2CA2NLRP3ALDH1A1 | |
| SCHEMBL26651827 | 0.79 | GABRA1 (0.47) | GABRA1GABRB2CA2NLRP3ALDH1A1 | |
| SCHEMBL7574017 | 0.77 | HTR1D (0.41) | GABRA1GABRB2TSHRTDP1ATM | |
| SCHEMBL26652064 | 0.75 | GABRA1 (0.44) | GABRA1GABRB2CA2NLRP3ALDH1A1 | |
| SCHEMBL17307162 | 0.74 | GABRA1 (0.55) | GABRA1GABRB2CA2NLRP3ALDH1A1 | |
| SCHEMBL14236812 | 0.74 | GABRA1 (0.54) | GABRA1GABRB2CA2NLRP3ALDH1A1 | |
| SCHEMBL26651800 | 0.71 | GABRA1 (0.50) | GABRA1GABRB2CA2NLRP3ALDH1A1 | |
| SCHEMBL3916579 | 0.71 | GABRA1 (0.50) | GABRA1GABRB2CA2NLRP3ALDH1A1 | |
| SCHEMBL27692244 | 0.70 | GABRA1 (0.50) | GABRA1GABRB2CA2NLRP3ALDH1A1 | |
| SCHEMBL30640998 | 0.70 | GABRA1 (0.50) | GABRA1GABRB2CA2NLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334408-A1 | REACTIVE MESOGENS | Merck Patent GmbH (DE) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022233908-A1 | REACTIVE MESOGENS | MERCK PATENT GMBH (DE) | 2022-11-10 | — | — | WO | disclosed |