Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.33 |
| ▸ | CPT1A | P50416 | 3/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.33 |
| ▸ | CPT2 | P23786 | 2/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186615 | 0.88 | GRIN2B (0.42) | GRIN2B | |
| SCHEMBL186829 | 0.74 | AOC3 (0.44) | CCNT1CDK9MAPK1 | |
| SCHEMBL2181332 | 0.73 | USP2 (0.39) | GRM5RIPK1 | |
| SCHEMBL186614 | 0.73 | PIM1 (0.40) | SLC6A7CCNT1CDK9ENPP2MAPK1 | |
| SCHEMBL2178411 | 0.72 | DPP4 (0.49) | — | |
| SCHEMBL2180949 | 0.72 | GRM5 (0.48) | GRM5 | |
| SCHEMBL300739 | 0.70 | CNR1 (0.45) | MAPK1CNR1 | |
| SCHEMBL186388 | 0.69 | PARP1 (0.36) | GRIN2BCCNT1CDK9MAPK1 | |
| SCHEMBL2179315 | 0.67 | MAPT (0.45) | — | |
| SCHEMBL2177967 | 0.67 | TDO2 (0.46) | CCNT1CDK9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297148-B1 | NOVEL DERIVATIVES OF (BRIDGED PIPERAZINYL)-1-ALCANONE AND USE THEREOF AS P75 INHIBITORS | SANOFI SA (FR) | 2012-01-04 | — | — | EP | claimed |