SCHEMBL30064584

SCHEMBL30064584

COc1cc(N[C@H]2[C@H]3OC[C@](CO)(O3)[C@H](O)[C@@H]2O)nc(C(F)(F)F)n1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ASGR1 P07306 15/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27180318 1.00 ASGR1 (0.47) ASGR1
SCHEMBL27180633 0.83 ASGR1 (0.47) ASGR1
SCHEMBL26902082 0.83 ASGR1 (0.45) ASGR1
SCHEMBL24724816 0.81 ASGR1 (0.33) ASGR1
SCHEMBL25867071 0.77 ASGR1 (0.47) ASGR1
SCHEMBL25872130 0.77 ASGR1 (0.50) ASGR1
SCHEMBL25872119 0.75 ASGR1 (0.45) ASGR1
SCHEMBL30063180 0.75 ASGR1 (0.52) ASGR1
SCHEMBL24725263 0.75 ASGR1 (0.52) ASGR1
SCHEMBL26879879 0.75 ASGR1 (0.52) ASGR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022235699-A2 POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2022-11-10 — — WO disclosed
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