SCHEMBL30065573

SCHEMBL30065573

COc1ccc(-n2c(C)nnc2N2C[C@@H]3C[C@]3(c3ccc(F)cc3Cl)C2)cn1

nearest known ligand 0.82

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OXTR P30559 19/20 0.82
AVPR1A P37288 17/20 0.82
AVPR1B P47901 6/20 0.79
AVPR2 P30518 6/20 0.79
KCNH2 Q12809 2/20 0.79
CYP3A4 P08684 1/20 0.79
CYP2C19 P33261 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21525959 1.00 OXTR (0.82) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL21525960 1.00 OXTR (0.82) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL30065741 0.90 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL21525951 0.90 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL30065699 0.89 OXTR (0.78) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL30065787 0.89 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL20345625 0.89 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL21525952 0.89 OXTR (0.78) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL21525957 0.89 OXTR (0.85) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL20345732 0.89 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149961-B Azabicyclo-substituted triazole derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2022-11-22 CN disclosed