SCHEMBL30065592

SCHEMBL30065592

COCc1nnc(N2C[C@H]3C[C@@]3(c3ccc(F)cc3Cl)C2)n1-c1ccc(OC)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OXTR P30559 20/20 1.00
AVPR1A P37288 12/20 1.00
AVPR1B P47901 6/20 1.00
AVPR2 P30518 6/20 1.00
KCNH2 Q12809 2/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2C19 P33261 1/20 1.00
TACR1 P25103 1/20 0.66
OPRK1 P41145 1/20 0.66
GHSR Q92847 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009729 1.00 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL20345732 1.00 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL30009620 1.00 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL20345671 1.00 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL20345677 1.00 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
Hydrochloric Acid SCHEMBL30010199 0.99 OXTR (0.98) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL21525958 0.95 OXTR (0.91) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL20345673 0.93 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL20345622 0.93 OXTR (0.87) OXTRAVPR1AAVPR1BAVPR2KCNH2
SCHEMBL30065786 0.93 OXTR (1.00) OXTRAVPR1AAVPR1BAVPR2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149961-B Azabicyclo-substituted triazole derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2022-11-22 CN disclosed