Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065642 | 1.00 | KMT2A (0.41) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL21857860 | 0.82 | KEAP1 (0.30) | — | |
| SCHEMBL22064233 | 0.82 | KEAP1 (0.35) | — | |
| SCHEMBL31157944 | 0.82 | KEAP1 (0.35) | — | |
| SCHEMBL16200786 | 0.81 | KEAP1 (0.36) | KDM4EPTGS2ALDH1A1 | |
| SCHEMBL30794314 | 0.81 | KEAP1 (0.50) | KMT2AMEN1KDM4ERAB9AALDH1A1 | |
| SCHEMBL9904591 | 0.81 | KEAP1 (0.50) | KMT2AMEN1KDM4ERAB9AALDH1A1 | |
| SCHEMBL16200788 | 0.79 | CYP1A2 (0.32) | — | |
| SCHEMBL9904936 | 0.78 | KEAP1 (0.32) | — | |
| SCHEMBL25027899 | 0.77 | PIK3CA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100402-A1 | KV3 MODULATORS | Autifony Therapeutics Limited (GB) | 2022-12-14 | — | — | EP | disclosed |