Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707759 | 1.00 | PARP1 (0.54) | PARP1PSMB5PIM1CSNK1A1CDK5 | |
| SCHEMBL2370234 | 0.81 | MAOB (0.39) | PARP1PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL5534959 | 0.78 | PARP1 (0.56) | PARP1PSMB5KDM4EHSD17B10MAPT | |
| SCHEMBL9130084 | 0.77 | MAOA (0.52) | KDM4EHSD17B10MAPTMAOAMAOB | |
| SCHEMBL12178135 | 0.76 | PARP1 (0.54) | PARP1PSMB5ADRA2AADRA2BADRA2C | |
| SCHEMBL3976344 | 0.76 | PARP1 (0.54) | PARP1PSMB5ADRA2AKDM4EHSD17B10 | |
| SCHEMBL5534964 | 0.76 | PSMB5 (0.61) | PARP1PSMB5KDM4EHSD17B10MAPT | |
| SCHEMBL30779660 | 0.76 | PARP1 (0.54) | PARP1PSMB5ADRA2AKDM4EHSD17B10 | |
| SCHEMBL18331030 | 0.76 | PARP1 (0.54) | PARP1PSMB5ADRA2AKDM4EHSD17B10 | |
| SCHEMBL8948724 | 0.76 | PARP1 (0.59) | PARP1PSMB5PIM1CSNK1A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930620-A | Tetrafused ring compound, preparation method, pharmaceutical composition and application thereof | 和径医药科技（上海）有限公司 | 2025-05-06 | — | — | CN | disclosed |
| EP-4337198-A1 | POLO LIKE KINASE 4 INHIBITORS | Oric Pharmaceuticals, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| WO-2022240876-A1 | POLO LIKE KINASE 4 INHIBITORS | ORIC PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |