Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | MST1R | Q04912 | 1/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25260852 | 1.00 | PIM1 (0.53) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL24886285 | 0.82 | PARP10 (0.56) | MAP2K1PARP10PARP1F7F3 | |
| SCHEMBL11346836 | 0.81 | MEN1 (0.44) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL24147834 | 0.78 | CLK4 (0.53) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL25411512 | 0.78 | CLK4 (0.53) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL1334392 | 0.78 | CLK4 (0.53) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL31458870 | 0.77 | CDK5 (0.49) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL1335593 | 0.75 | LRRK2 (0.50) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL25415363 | 0.75 | CDK5 (0.50) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL30598935 | 0.75 | CDK5 (0.50) | PIM1CSNK1A1CDK5ROCK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184152-A1 | FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-09-09 | — | — | WO | disclosed |