Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | MST1R | Q04912 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27085865 | 0.87 | PIM1 (0.49) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL22990374 | 0.84 | PARP10 (0.51) | PARP10PARP11MAP2K1 | |
| SCHEMBL29698311 | 0.84 | PARP10 (0.51) | PARP10PARP11MAP2K1 | |
| SCHEMBL25260852 | 0.77 | PIM1 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL30068832 | 0.77 | PIM1 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL21199913 | 0.76 | GRM2 (0.35) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL25412348 | 0.76 | HRH3 (0.44) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL25411512 | 0.74 | CLK4 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL24147834 | 0.74 | CLK4 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL25959471 | 0.72 | PIM1 (0.38) | CDK5DYRK1ACLK4PIM1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067227-A1 | PREPARATION METHOD FOR CBL-B REGULATOR, AND USE | 浙江华海药业股份有限公司 | 2025-04-03 | — | — | WO | disclosed |