SCHEMBL30068985

SCHEMBL30068985

C=Cc1nc(Cl)cc2c1COCC2

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
WNT3A P56704 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25302687 1.00 WNT3A (0.30) WNT3ATNKS2
SCHEMBL25258434 0.84 WNT3A (0.35) WNT3ATNKS2
SCHEMBL903618 0.78 WNT3A (0.33) WNT3ATNKS2
SCHEMBL25258762 0.75 WNT3A (0.30) WNT3ATNKS2
SCHEMBL31150847 0.69 PDCD1 (0.34)
SCHEMBL30068646 0.69 KDM4E (0.35)
SCHEMBL25257483 0.69 KDM4E (0.35)
SCHEMBL25841789 0.66 WNT3A (0.33) WNT3ATNKS2
SCHEMBL31517914 0.65 TNKS2 (0.42) WNT3ATNKS2
SCHEMBL25302129 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118488947-A Condensed ring substituted six-membered heterocyclic compound, preparation method and application thereof 劲方医药科技(上海)有限公司 2024-08-13 CN disclosed
WO-2023131122-A1 FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 劲方医药科技(上海)有限公司 2023-07-13 WO disclosed
WO-2022184152-A1 FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 劲方医药科技(上海)有限公司 2022-09-09 WO disclosed