SCHEMBL30069005

SCHEMBL30069005

CC(C)(O)c1cc(C(=O)O)ccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 6/20 0.53
KDM5C P41229 6/20 0.53
KDM5B Q9UGL1 5/20 0.53
KDM4A O75164 5/20 0.53
KDM4E B2RXH2 4/20 0.53
KDM2A Q9Y2K7 4/20 0.53
KDM3A Q9Y4C1 4/20 0.53
KDM6B O15054 3/20 0.53
KDM5A P29375 3/20 0.53
ALDH1A1 P00352 2/20 0.53
TET3 O43151 1/20 0.53
BBOX1 O75936 1/20 0.53
MAPT P10636 1/20 0.53
ASPH Q12797 1/20 0.53
KDM4D Q6B0I6 1/20 0.53
TET2 Q6N021 1/20 0.53
ALKBH5 Q6P6C2 1/20 0.53
KDM7A Q6ZMT4 1/20 0.53
KDM8 Q8N371 1/20 0.53
TET1 Q8NFU7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16095006 1.00 KDM4C (0.53) KDM4CKDM5CKDM5BKDM4AKDM4E
SCHEMBL1759647 0.87 LMNA (0.62) KDM4CKDM5CKDM5BKDM4AKDM4E
SCHEMBL16094544 0.85 KDM4C (0.53) KDM4CKDM5CKDM5BKDM4AKDM4E
SCHEMBL9444888 0.85 LMNA (0.45) ALDH1A1LMNASMN1; SMN2HTTNPC1
SCHEMBL16036217 0.84 KDM4C (0.52) KDM4CKDM5CKDM5BKDM4AKDM4E
SCHEMBL30893039 0.84 KDM4C (0.52) KDM4CKDM5CKDM5BKDM4AKDM4E
SCHEMBL25701470 0.81 KDM4C (0.51) KDM4CKDM5CKDM5BKDM4AKDM4E
SCHEMBL16121175 0.81 KDM4E (0.55) KDM4CKDM5CKDM5BKDM4EKDM2A
SCHEMBL25340658 0.80 KDM4C (0.47) KDM4CKDM5CKDM5BKDM4AKDM4E
SCHEMBL3942944 0.80 KDM4C (0.47) KDM4CKDM5CKDM5BKDM4AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676918-A1 COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS Nanjing Immunophage Biomedical Co., Ltd. (CN) 2026-01-14 EP disclosed
WO-2024208303-A1 COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) 2024-10-10 WO disclosed
WO-2022184152-A1 FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 劲方医药科技(上海)有限公司 2022-09-09 WO disclosed