Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480031 | 0.77 | MAOB (0.39) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL23593943 | 0.76 | AKR1C1 (0.70) | KDM4EALDH1A1HPGDMAPTAKR1C1 | |
| SCHEMBL6689798 | 0.76 | AKR1C1 (0.70) | KDM4EALDH1A1HPGDMAPTAKR1C1 | |
| SCHEMBL2836206 | 0.76 | AKR1C1 (0.70) | KDM4EALDH1A1HPGDMAPTAKR1C1 | |
| SCHEMBL29006674 | 0.76 | MAPT (0.68) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL29006676 | 0.76 | MAPT (0.68) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL11529553 | 0.75 | GAA (0.60) | ALDH1A1MAPTRAB9AGAAMAOB | |
| SCHEMBL11019288 | 0.72 | AKR1C1 (0.55) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11019290 | 0.72 | AKR1C1 (0.55) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL20273256 | 0.72 | PARP10 (0.59) | ALDH1A1MAOBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351553-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH (DE) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022258792-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2022-12-15 | — | — | WO | disclosed |