Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652897 | 0.77 | NPC1 (0.48) | PTGS2PLA2G4AALDH1A1KDM4ENPC1 | |
| SCHEMBL30069262 | 0.77 | KDM4E (0.49) | MAOBPTGS2MAOACA12CA2 | |
| SCHEMBL17844700 | 0.68 | ALDH1A1 (0.55) | PLA2G4AALDH1A1MAPTRAB9ARBBP9 | |
| SCHEMBL19974187 | 0.66 | ALDH1A1 (0.48) | PLA2G4AALDH1A1MAPTRBBP9KMT2A | |
| SCHEMBL26208697 | 0.66 | MAOB (0.49) | MAOBPTGS2MAOACA12CA2 | |
| SCHEMBL20273256 | 0.65 | PARP10 (0.59) | MAOBCA12CA2CA9CA1 | |
| SCHEMBL825205 | 0.64 | MAOA (0.54) | MAOBPTGS2MAOACA12CA2 | |
| SCHEMBL20665981 | 0.64 | SAE1 (0.47) | CA2CA1CA4CA7HDAC3 | |
| SCHEMBL540825 | 0.64 | NR1H4 (0.62) | MAOBPTGS2MAOAHDAC3HDAC2 | |
| SCHEMBL18153585 | 0.64 | KMT2A (0.53) | PLA2G4AALDH1A1KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452956-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023118373-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-06-29 | — | — | WO | disclosed |