Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467736 | 1.00 | CTSL (0.43) | CTSLMEN1KMT2ANPSR1HTT | |
| SCHEMBL30069333 | 1.00 | CTSL (0.43) | CTSLMEN1KMT2ANPSR1HTT | |
| SCHEMBL27929780 | 0.94 | MEN1 (0.44) | CTSLMEN1KMT2ANPSR1HTT | |
| SCHEMBL27929768 | 0.94 | MEN1 (0.44) | CTSLMEN1KMT2ANPSR1HTT | |
| SCHEMBL1467693 | 0.94 | MEN1 (0.44) | CTSLMEN1KMT2ANPSR1HTT | |
| SCHEMBL14638218 | 0.92 | MEN1 (0.43) | CTSLMEN1KMT2ABACE1SYK | |
| SCHEMBL14650130 | 0.92 | MEN1 (0.43) | CTSLMEN1KMT2ABACE1SYK | |
| SCHEMBL7500297 | 0.90 | MEN1 (0.47) | CTSLMEN1KMT2ANPSR1HTT | |
| SCHEMBL14828963 | 0.89 | SYK (0.46) | CTSLMEN1KMT2ANPSR1HTT | |
| SCHEMBL30923062 | 0.89 | CTSL (0.44) | CTSLMEN1KMT2ABACE1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237649-A1 | EXOCYCLIC AMINO QUINAZOLINE DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |