⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5173939 | 0.92 | — | — | |
| SCHEMBL6681595 | 0.73 | — | — | |
| SCHEMBL5084465 | 0.67 | — | — | |
| SCHEMBL3384131 | 0.65 | — | — | |
| SCHEMBL9644878 | 0.64 | LTA4H (0.32) | — | |
| SCHEMBL11772384 | 0.63 | — | — | |
| SCHEMBL4302559 | 0.63 | — | — | |
| SCHEMBL11773650 | 0.63 | — | — | |
| SCHEMBL193409 | 0.63 | — | — | |
| SCHEMBL9762100 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970495-B2 | Indolizine derivatives and their application in medicine | KIND PHARMACEUTICAL (CN) | 2024-04-30 | — | — | US | disclosed |
| US-11945817-B2 | Indolizine derivatives and their application in medicine | KIND PHARMACEUTICAL (CN) | 2024-04-02 | — | — | US | disclosed |
| US-20230257379-A1 | INDOLIZINE DERIVATIVES AND THEIR APPLICATION IN MEDICINE | KIND PHARMACEUTICAL (CN) | 2023-08-17 | — | — | US | disclosed |
| US-11718615-B2 | Heterocyclic compounds and their application in medicine | KIND PHARMACEUTICAL (CN) | 2023-08-08 | — | — | US | disclosed |
| US-20230242527-A1 | INDOLIZINE DERIVATIVES AND THEIR APPLICATION IN MEDICINE | KIND PHARMACEUTICAL (CN) | 2023-08-03 | — | — | US | disclosed |
| US-11655249-B2 | Indolizine derivatives and their application in medicine | KIND PHARMACEUTICAL (CN) | 2023-05-23 | — | — | US | disclosed |
| EP-3613742-B1 | INDOLIZINE DERIVATIVES AND APPLICATION THEREOF IN MEDICINE | KIND PHARMACEUTICAL (CN) | 2022-12-07 | — | — | EP | disclosed |
| CN-114835705-A | Heterocyclic compound and application thereof in medicine | 杭州安道药业有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-109776523-B | Heterocyclic compound and application thereof in medicine | 杭州安道药业有限公司 | 2022-04-15 | — | — | CN | disclosed |
| US-11236088-B2 | Heterocyclic compounds and their application in medicine | KIND PHARMACEUTICAL (CN) | 2022-02-01 | — | — | US | disclosed |
| WO-2003068785-A1 | MONO- AND BIACYLPHOSPHINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-21 | — | — | WO | disclosed |
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | disclosed |
| US-20030114458-A1 | Antibacterial agents | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | disclosed |
| CN-1425008-A | 3-aminoquinazolin-2, 4-dione antibacterial agents | WARNER LAMBERT CO (US) | 2003-06-18 | — | — | CN | disclosed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | disclosed |
| WO-2002096908-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-05 | — | — | WO | disclosed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |
| CN-1030604-C | Heterocyclic compounds | GLAXO SPA (IT) | 1996-01-03 | — | — | CN | disclosed |
| CN-1064682-A | The preparation method of heterogeneous ring compound | GLAXO SPA (IT) | 1992-09-23 | — | — | CN | disclosed |