Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 9/20 | 1.00 |
| ▸ | BRD4 | O60885 | 13/20 | 0.81 |
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.77 |
| ▸ | TAF1 | P21675 | 4/20 | 0.72 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.71 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.71 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.71 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.71 |
| ▸ | EP300 | Q09472 | 1/20 | 0.71 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.71 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.71 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.71 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17749863 | 1.00 | CECR2 (1.00) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL30073254 | 0.94 | CECR2 (1.00) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL17749735 | 0.94 | CECR2 (1.00) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL29482208 | 0.89 | BRD4 (1.00) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL17758432 | 0.89 | BRD4 (0.85) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL17749840 | 0.89 | BRD4 (1.00) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL17749719 | 0.89 | BRD4 (1.00) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL17748869 | 0.87 | BRD9 (1.00) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL17758435 | 0.87 | BRD9 (0.85) | CECR2BRD4BRD9TAF1TRIM24 | |
| SCHEMBL17748956 | 0.85 | CECR2 (1.00) | CECR2BRD4BRD9TAF1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583947-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-10 | — | — | CN | claimed |
| CN-116003409-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-107207493-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115583947-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-10 | — | — | CN | disclosed |