SCHEMBL30074698

SCHEMBL30074698

O=C(O)COCNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
EPHX2 P34913 1/20 0.46
FABP5 Q01469 3/20 0.44
FABP7 O15540 2/20 0.44
CASP3 P42574 2/20 0.43
OPRD1 P41143 1/20 0.43
MDM4 O15151 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16867594 1.00 KMT2A (0.56) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL31217953 0.99 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL29609426 0.99 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL29101959 0.95 KMT2A (0.54) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL29233234 0.92 KMT2A (0.53) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL38657876 0.91 KMT2A (0.62) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL30620554 0.89 KMT2A (0.61) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL20628608 0.88 KMT2A (0.46) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL27432171 0.88 KMT2A (0.54) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL31217947 0.87 KMT2A (0.48) KMT2AEPHX2FABP5FABP7OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325687-A1 CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST MABSOFT THERAPEUTICS SHANGHAI CO LTD (CN) 2025-10-23 US disclosed
EP-4593824-A2 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS Nuvation Bio Inc. (US) 2025-08-06 EP disclosed
WO-2024235132-A9 COMPOUND HAVING BIOLOGICAL ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2025-06-19 WO disclosed
WO-2024235128-A9 ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2025-06-19 WO disclosed
EP-4508061-A1 CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST Mabsoft Therapeutics (Shanghai) Co., Ltd. (CN) 2025-02-19 EP disclosed
WO-2024235132-A1 COMPOUND HAVING BIOLOGICAL ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-11-21 WO disclosed
WO-2024235128-A1 ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-11-21 WO disclosed
US-20240026030-A1 METHOD OF TREATING CANCER COMPRISING ADMINISTRATION OF ANTI-HER2 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-01-25 US disclosed
WO-2024008102-A1 LINKER FOR CONJUGATION WUXI XDC (SHANGHAI) CO., LTD. (CN) 2024-01-11 WO disclosed
US-20230330248-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-10-19 US disclosed
WO-2023198195-A1 CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST MABSOFT THERAPEUTICS (SHANGHAI) CO., LTD. (CN) 2023-10-19 WO disclosed
EP-4115909-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2023-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240026030-A1 METHOD OF TREATING CANCER COMPRISING ADMINISTRATION OF ANTI-HER2 ANTIBODY-DRUG CONJUGATE ERBB2, EGFR, H1-2 KMT2A 386/4885EPHX2 2136/4885FABP5 2840/4885
US-20230330248-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE STING1, CGAS, TLR9 KMT2A 2926/4885EPHX2 1097/4885FABP5 3438/4885
US-20250325687-A1 CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST TLR3, TLR7, TLR8 KMT2A 2191/4885EPHX2 3659/4885FABP5 2154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.