SCHEMBL30620554

SCHEMBL30620554

O=C(O)CCOCNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
EPHX2 P34913 1/20 0.45
FABP7 O15540 2/20 0.44
FABP5 Q01469 2/20 0.44
CASP3 P42574 2/20 0.43
OPRD1 P41143 1/20 0.43
TLR2 O60603 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16757545 0.90 KMT2A (0.60) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29975343 0.90 KMT2A (0.60) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29101959 0.90 KMT2A (0.54) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL30074698 0.89 KMT2A (0.56) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL16867594 0.89 KMT2A (0.56) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29262943 0.89 KMT2A (0.59) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29609426 0.88 KMT2A (0.55) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31217953 0.88 KMT2A (0.55) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL30716476 0.88 KMT2A (0.52) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31478725 0.87 KMT2A (0.57) KMT2AEPHX2FABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116789733-B Coupling linker 上海药明合联生物技术有限公司 2025-01-24 CN disclosed
CN-118955615-A Coupling linker 上海药明合联生物技术有限公司 2024-11-15 CN disclosed
CN-118955614-A Coupling linker 上海药明合联生物技术有限公司 2024-11-15 CN disclosed
WO-2024008102-A1 LINKER FOR CONJUGATION WUXI XDC (SHANGHAI) CO., LTD. (CN) 2024-01-11 WO disclosed
CN-116789733-A Coupling linker 上海药明合联生物技术有限公司 2023-09-22 CN disclosed