Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12602244 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1TDP1KMT2A | |
| SCHEMBL25239580 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL30074755 | 0.74 | KMT2A (0.42) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL28332298 | 0.74 | KMT2A (0.53) | ALDH1A1HPGDKDM4EMAPTL3MBTL1 | |
| SCHEMBL9500368 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EMAPTL3MBTL1 | |
| SCHEMBL31686158 | 0.72 | SMN1; SMN2 (0.42) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL3703857 | 0.72 | SMN1; SMN2 (0.42) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL21538738 | 0.72 | TDP1 (0.40) | ALDH1A1KDM4ETDP1KMT2AGAA | |
| SCHEMBL15903864 | 0.71 | NCEH1 (0.39) | ALDH1A1HPGDKDM4EMAPTL3MBTL1 | |
| SCHEMBL15903547 | 0.71 | HPRT1 (0.44) | ALDH1A1HPGDKDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087854-A1 | NEUROACTIVE STEROIDS AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Brii Biosciences, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |