Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21140644 | 0.80 | CYP3A4 (0.32) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL20260096 | 0.77 | CYP3A4 (0.34) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL9801270 | 0.74 | MEN1 (0.37) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL20257616 | 0.74 | CYP3A4 (0.32) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3923862 | 0.74 | SMN1; SMN2 (0.32) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11202459 | 0.74 | SLC6A2 (0.30) | — | |
| SCHEMBL24464156 | 0.73 | TSHR (0.41) | ALDH1A1TDP1 | |
| SCHEMBL78076 | 0.73 | TSHR (0.41) | ALDH1A1TDP1 | |
| SCHEMBL13604142 | 0.73 | TSHR (0.41) | ALDH1A1TDP1 | |
| SCHEMBL12659394 | 0.73 | TSHR (0.41) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4114566-A1 | CATALYST COMPOSITION FOR POLYURETHANES | Momentive Performance Materials Inc. (US) | 2023-01-11 | — | — | EP | claimed |