Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21140590 | 0.82 | KMT2A (0.33) | — | |
| SCHEMBL31249882 | 0.81 | — | — | |
| SCHEMBL20260096 | 0.80 | CYP3A4 (0.34) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30075593 | 0.80 | SMN1; SMN2 (0.33) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL13999837 | 0.80 | SLC6A2 (0.32) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL31249909 | 0.78 | — | — | |
| SCHEMBL20257616 | 0.78 | CYP3A4 (0.32) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL20257560 | 0.77 | RAB9A (0.40) | — | |
| SCHEMBL17519182 | 0.76 | — | — | |
| SCHEMBL23869469 | 0.74 | CYP3A4 (0.38) | CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548857-B2 | Biodegradable compound, lipid particle, composition comprising lipid particle, and kit | KABUSHIKI KAISHA TOSHIBA (JP) | 2023-01-10 | — | — | US | disclosed |
| WO-2022254848-A1 | FLOW CHANNEL STRUCTURE FOR REMOVING FOREIGN SUBSTANCE, METHOD FOR REMOVING FOREIGN SUBSTANCE, AND METHOD FOR MANUFACTURING LIPID PARTICLES | KABUSHIKI KAISHA TOSHIBA (JP) | 2022-12-08 | — | — | WO | disclosed |
| EP-3842412-A1 | BIODEGRADABLE COMPOUND, LIPID PARTICLES, COMPOSITION CONTAINING LIPID PARTICLES, AND KIT | Kabushiki Kaisha Toshiba (JP) | 2021-06-30 | — | — | EP | disclosed |
| US-10766869-B2 | Triazoles for the treatment of demyelinating dieases | VERTEX PHARMACEUTCALS INCORPORATED (US) | 2020-09-08 | — | — | US | disclosed |
| US-20200270217-A1 | BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT | KABUSHIKI KAISHA TOSHIBA (JP) | 2020-08-27 | — | — | US | disclosed |
| US-20190185436-A1 | TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES | VERTEX PHARMA (US) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548857-B2 | Biodegradable compound, lipid particle, composition comprising lipid particle, and kit | KIT, NPY1R, CCKAR | CYP3A4 3765/4885CYP2D6 2682/4885CYP2C19 1897/4885 |
| US-10766869-B2 | Triazoles for the treatment of demyelinating dieases | PMP22, MYT1, IDE | CYP3A4 713/4885CYP2D6 984/4885CYP2C19 1068/4885 |
| US-20190185436-A1 | TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES | PMP22, MYT1, IKZF3 | CYP3A4 761/4885CYP2D6 1674/4885CYP2C19 1009/4885 |
| US-20200270217-A1 | BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT | KIT, NPY1R, CCKAR | CYP3A4 3765/4885CYP2D6 2682/4885CYP2C19 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.