SCHEMBL30076004

SCHEMBL30076004

CCS(=O)(=O)c1ccc([C@H](CO)NC(=O)c2ccc3c(c2)cc(Cc2ccc(Cl)cc2C(F)(F)F)n3CCF)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RORC P51449 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20634735 1.00 RORC (1.00) RORC
SCHEMBL20634736 1.00 RORC (1.00) RORC
SCHEMBL20635535 1.00 RORC (1.00) RORC
SCHEMBL29465608 1.00 RORC (1.00) RORC
SCHEMBL22227717 0.95 RORC (0.91) RORC
SCHEMBL22227718 0.95 RORC (0.91) RORC
SCHEMBL22227727 0.94 RORC (0.89) RORC
SCHEMBL22227726 0.94 RORC (0.89) RORC
SCHEMBL22227710 0.94 RORC (0.88) RORC
SCHEMBL22227709 0.94 RORC (0.88) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109963836-B Deuterium atom substituted indole carboxamide derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2022-11-22 CN disclosed