Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924141 | 1.00 | TLR8 (0.48) | TLR8TLR7KCNH2ADORA2AADORA1 | |
| SCHEMBL19924139 | 1.00 | TLR8 (0.48) | TLR8TLR7KCNH2ADORA2AADORA1 | |
| SCHEMBL19924183 | 0.88 | TLR8 (0.54) | TLR8TLR7KCNH2ADORA2AADORA1 | |
| SCHEMBL19924181 | 0.88 | TLR8 (0.54) | TLR8TLR7KCNH2ADORA2AADORA1 | |
| SCHEMBL30076088 | 0.88 | TLR8 (0.54) | TLR8TLR7KCNH2ADORA2AADORA1 | |
| SCHEMBL19924195 | 0.88 | TLR8 (0.36) | TLR8TLR7 | |
| SCHEMBL19924197 | 0.88 | TLR8 (0.36) | TLR8TLR7 | |
| SCHEMBL21226297 | 0.86 | TLR8 (0.44) | TLR8TLR7KCNH2 | |
| SCHEMBL23836683 | 0.84 | TLR8 (0.39) | TLR8TLR7 | |
| SCHEMBL19924169 | 0.83 | TLR8 (0.52) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923106-B | toll-like receptor modulator compounds | 吉利德科学公司 | 2022-09-13 | — | — | CN | disclosed |