Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | LATS1 | O95835 | 12/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21226297 | 0.90 | TLR8 (0.44) | TLR8TLR7 | |
| SCHEMBL19924277 | 0.85 | TLR8 (0.47) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL19924276 | 0.85 | TLR8 (0.47) | TLR8TLR7LATS1LATS2 | |
| SCHEMBL19924141 | 0.84 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL19924139 | 0.84 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL30076056 | 0.84 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL30076088 | 0.78 | TLR8 (0.54) | TLR8TLR7 | |
| SCHEMBL19924181 | 0.78 | TLR8 (0.54) | TLR8TLR7 | |
| SCHEMBL19924183 | 0.78 | TLR8 (0.54) | TLR8TLR7 | |
| SCHEMBL19924194 | 0.76 | KDM4C (0.43) | LATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124487-B2 | Toll like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2021-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124487-B2 | Toll like receptor modulator compounds | TLR8, TLR3, TLR6 | TLR8 1/4885TLR7 9/4885LATS1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.