Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10085751 | 0.88 | HTR1A (0.57) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL14275911 | 0.85 | HTR1A (0.59) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL10086372 | 0.80 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL11316620 | 0.77 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL10085905 | 0.76 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL22971568 | 0.76 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL10086530 | 0.73 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| Acetic Acid SCHEMBL3681231 | 0.73 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL11316854 | 0.72 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| Propionic Acid SCHEMBL1764372 | 0.72 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220347305-A1 | CONTROLLED RELEASE DRUG DIMERS | RIPPLE THERAPEUTICS CORPORATION (CA) | 2022-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220347305-A1 | CONTROLLED RELEASE DRUG DIMERS | ABCB1, IAPP, CFTR | NPC1 299/4885RAB9A 1682/4885SMN1; SMN2 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.