Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 7/20 | 0.34 |
| ▸ | IDH2 | P48735 | 6/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15347711 | 1.00 | KMT2A (0.42) | KMT2AOPRK1SMPD3JAK2HTR3E | |
| SCHEMBL18158119 | 0.81 | CCR1 (0.56) | KMT2AOPRK1SMPD3ALDH1A1NPY5R | |
| SCHEMBL15347467 | 0.80 | OPRK1 (0.35) | KMT2AOPRK1JAK2HTR3EHTR3B | |
| SCHEMBL30077011 | 0.80 | OPRK1 (0.35) | KMT2AOPRK1JAK2HTR3EHTR3B | |
| SCHEMBL28905996 | 0.80 | KMT2A (0.36) | KMT2AOPRK1SMPD3NPY5RPIN1 | |
| SCHEMBL30077058 | 0.78 | IDH1 (0.37) | KMT2AOPRK1HTR3EHTR3BALDH1A1 | |
| SCHEMBL30077134 | 0.78 | PDK2 (0.38) | KMT2AOPRK1JAK2ALDH1A1IDH1 | |
| SCHEMBL15347407 | 0.78 | PDK2 (0.38) | KMT2AOPRK1JAK2ALDH1A1IDH1 | |
| SCHEMBL15347246 | 0.78 | IDH1 (0.37) | KMT2AOPRK1HTR3EHTR3BALDH1A1 | |
| SCHEMBL12685281 | 0.74 | KDM4E (0.36) | KMT2AOPRK1SMPD3JAK2HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220348577-A1 | CXCR4 Receptor Antagonists | PROXIMAGEN LLC (US) | 2022-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220348577-A1 | CXCR4 Receptor Antagonists | CXCR4, CXCR1, CXCR2 | KMT2A 3673/4885OPRK1 71/4885SMPD3 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.