Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 5/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA7 | P43166 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | CA6 | P23280 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SELL | P14151 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24885905 | 1.00 | TPMT (0.59) | TPMTTTRCA12CA1CA2 | |
| SCHEMBL1071876 | 0.87 | TTR (0.62) | TPMTTTRCA12CA1CA2 | |
| SCHEMBL1919748 | 0.84 | CA12 (0.64) | TPMTTTRCA12CA1CA2 | |
| Water SCHEMBL4387068 | 0.82 | CA12 (0.61) | TPMTTTRCA12CA1CA2 | |
| Water SCHEMBL4387073 | 0.82 | CA12 (0.61) | TPMTTTRCA12CA1CA2 | |
| SCHEMBL5631374 | 0.81 | TTR (0.56) | TPMTTTRCA12CA1CA2 | |
| SCHEMBL29710249 | 0.81 | TTR (0.56) | TPMTTTRCA12CA1CA2 | |
| SCHEMBL27091773 | 0.79 | TTR (0.54) | TPMTTTRCA12CA1CA2 | |
| SCHEMBL13199302 | 0.78 | CA12 (0.56) | TPMTTTRCA12CA1CA2 | |
| SCHEMBL29373087 | 0.78 | TTR (0.78) | TPMTTTRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283369-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-01-12 | — | — | WO | disclosed |