Sugi Predict

Sugi Predict / Compounds / SCHEMBL5631374

SCHEMBL5631374

SCHEMBL5631374

Cc1cc(C(=O)O)cc(Br)c1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 2/20 0.56
▸ TPMT P51580 3/20 0.48
▸ HCAR1 Q9BXC0 1/20 0.42
▸ GPR35 Q9HC97 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ CA12 O43570 2/20 0.39
▸ CA1 P00915 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA7 P43166 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ CA14 Q9ULX7 2/20 0.39
▸ THRA P10827 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ MYC P01106 1/20 0.39
▸ ESR1 P03372 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ PTPN7 P35236 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ NOTUM Q6P988 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29710249 1.00 TTR (0.56) TTRTPMTHCAR1GPR35PKM
SCHEMBL1071876 0.89 TTR (0.62) TTRTPMTHCAR1GPR35PKM
SCHEMBL1572119 0.84 TPMT (0.59) TTRTPMTHCAR1GPR35PKM
SCHEMBL12659328 0.83 NPC1 (0.45) TTRHSD17B10TSHRKMT2AALDH1A1
SCHEMBL6908978 0.81 TPMT (0.56) TTRTPMTHCAR1GPR35PKM
SCHEMBL6909433 0.81 TPMT (0.56) TTRTPMTHCAR1GPR35PKM
SCHEMBL6912583 0.81 TPMT (0.56) TTRTPMTHCAR1GPR35PKM
Hydrochloric Acid SCHEMBL10831952 0.81 TPMT (0.56) TTRTPMTHCAR1GPR35PKM
SCHEMBL6916910 0.81 TPMT (0.56) TTRTPMTHCAR1GPR35PKM
SCHEMBL6909846 0.81 TPMT (0.56) TTRTPMTHCAR1GPR35PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651955-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2025-11-26 — — EP disclosed
WO-2024153947-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2024-07-25 — — WO disclosed
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CORNELL UNIVERSITY (US) 2024-04-30 — — US disclosed
US-20230331745-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2023-10-19 — — US disclosed
US-11767332-B2 Glucose-sensitive albumin-binding derivatives NOVO NORDISK A/S (DK) 2023-09-26 — — US disclosed
US-20230149414-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 — — US disclosed
US-20230149414-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 — — US disclosed
US-20230149414-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 — — US disclosed
CN-115484948-A Compound and use thereof 福宏治疗公司 2022-12-16 — — CN disclosed
CN-108698992-B 2-cyanoisoindoline derivatives for the treatment of cancer 特殊治疗有限公司 2022-04-19 — — CN disclosed
WO-2017158388-A1 2-CYANOISOINDOLINE DERIVATIVES FOR TREATING CANCER MISSION THERAPEUTICS LIMITED (GB) 2017-09-21 — — WO disclosed
US-20140194383-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2014-07-10 — — US disclosed
US-20140194383-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2014-07-10 — — US disclosed
EP-2694707-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME Cornell University (US) 2014-02-12 — — EP disclosed
WO-2013058824-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2013-04-25 — — WO disclosed
WO-2013058824-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2013-04-25 — — WO disclosed
US-7208629-B2 5′-Carbamoyl-1,1-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors GLAXO GROUP LIMITED (GB) 2007-04-24 — — US disclosed
US-20040267012-A1 5'-Carbamoyl-1,1-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors GLAXO GROUP LIMITED (GB) 2004-12-30 — — US disclosed
EP-0600084-A1 INDOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-06-08 — — EP disclosed
WO-1993003012-A1 INDOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CALCOCO2, MDN1, MBNL1 TTR 311/4885TPMT 3699/4885HCAR1 2457/4885
US-20230149414-A1 COMPOUNDS AND USES THEREOF VHL, CLN6, TFEB TTR 3059/4885TPMT 463/4885HCAR1 4259/4885
US-20040267012-A1 5'-Carbamoyl-1,1-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors MAPK4, GRK4, NR4A1 TTR 4555/4885TPMT 2628/4885HCAR1 149/4885
US-20230331745-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES ALB, DBI, FABP4 TTR 186/4885TPMT 4684/4885HCAR1 1150/4885
US-11767332-B2 Glucose-sensitive albumin-binding derivatives ALB, DBI, FABP4 TTR 186/4885TPMT 4684/4885HCAR1 1150/4885
US-20140194383-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CALCOCO2, MDN1, MBNL1 TTR 311/4885TPMT 3699/4885HCAR1 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.