Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209022 | 1.00 | BRAF (0.45) | BRAFL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL3880219 | 0.85 | L3MBTL1 (0.50) | BRAFL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL4252815 | 0.80 | L3MBTL1 (0.59) | BRAFL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL24316794 | 0.79 | L3MBTL1 (0.44) | BRAFL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL30078246 | 0.78 | MAP4K4 (0.44) | L3MBTL1ALDH1A1HPGDTNF | |
| SCHEMBL24885790 | 0.78 | MAP4K4 (0.44) | L3MBTL1ALDH1A1HPGDTNF | |
| SCHEMBL24885527 | 0.76 | BRAF (0.53) | BRAFL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL30078061 | 0.76 | BRAF (0.53) | BRAFL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL9922441 | 0.75 | KDM4E (0.58) | BRAFL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL30648059 | 0.75 | KDM4E (0.58) | BRAFL3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283369-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-01-12 | — | — | WO | disclosed |