Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Camphoric Acid SCHEMBL12084182 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL2513165 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL23643 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL1738809 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL52395 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL12308 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL7102028 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL12083956 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL7099871 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 | |
| Camphoric Acid SCHEMBL27486599 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337196-A1 | COCRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR | Loxo Oncology, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240920-A1 | COCRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR | LOXO ONCOLOGY, INC. (US) | 2022-11-17 | — | — | WO | disclosed |