Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12295342 | 1.00 | CCR1 (0.46) | CCR1CCR5CCR8HDAC6GRM5 | |
| SCHEMBL10140986 | 0.80 | CCR1 (0.44) | CCR1CCR5CCR8HDAC6GRM5 | |
| SCHEMBL16289566 | 0.80 | CCR1 (0.44) | CCR1CCR5CCR8HDAC6GRM5 | |
| SCHEMBL14129682 | 0.78 | GRM5 (0.53) | CCR1CCR5CCR8HDAC6GRM5 | |
| SCHEMBL3958689 | 0.78 | CCR1 (0.43) | CCR1CCR5CCR8HDAC6GRM5 | |
| SCHEMBL22270434 | 0.77 | ADRA2A (0.41) | GRM5ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL5740851 | 0.77 | MAPT (0.41) | GRM5MAPTCYP2A6 | |
| SCHEMBL3090594 | 0.76 | — | — | |
| SCHEMBL17039215 | 0.76 | GRM5 (0.54) | GRM5BTK | |
| SCHEMBL15991273 | 0.76 | ADRA2A (0.38) | GRM5ADRA2AADRA2BADRA2CPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052860-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-115052860-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2022-09-13 | — | — | CN | disclosed |